The iron-catalyst compound, cas is 102-54-5 name is Ferrocene, mainly used in chemical industry, its synthesis route is as follows.
Weigh 5.59g (30mmol) ferrocene was added to 250mL two-necked flask, and then weighed 24mL (254mmol) of acetic anhydride was added to the flask, and then weighed 7mL (including H3PO4 121mmol) 85% phosphoric acid was added slowly to the flask.Temperature was raised to 75 ~ 80C for about 10min, then the flask was immediately cooled in an ice bath, was added to the flask to about 30mL of ice water.After a short cooling with 25% NaOH solution to neutral, a large tan solid precipitated, cooling was continued for some time and the filter cake was washed with an amount of ice water, dry.The crude product is purified by column chromatography (dichloromethane / petroleum ether (60-90) eluting the solvent was evaporated to give an orange solid ferrocene ethyl ketone product 5.30g, yield 77.1% (ferrocene meter ), melting point 83 ~ 85C.
As the rapid development of chemical substances, we look forward to future research findings about 102-54-5
Reference£º
Patent; Huazhong Agricultural University; Ma, Jingzhong; Yan, Xinwen; Ma, Zhonghua; Jiang, Hong; Yang, Qiuhong; He, Mengli; (18 pag.)CN103626805; (2016); B;,
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