Ferrocenylacetic acid, cas is 1287-16-7, it is a common heterocyclic compound, the iron-catalyst compound, its synthesis route is as follows.
11-O-Nitro-azithromycin (0.25 mmol) was dissolved in dry dichloromethane (5 mL). To this was added EDCI (2 eq., 0.5 mmol) and 2-ferrocenyl acetic acid (1.1 eq., 0.28 mmol). The reaction was stirred overnight at room temperature. The solvent was removed in vacuo and the resulting white amorphous foam. The resulting crude product was purified by column chromatography with a gradient starting at 10 % of acetone in cyclohexane (0.2% Et3N)., 1287-16-7
As the rapid development of chemical substances, we look forward to future research findings about 1287-16-7
Reference£º
Patent; SYNOVO GMBH; PIETRZIK, Nikolas; BURNET, Michael, W.; BAEUERLEIN, Christiane; EGGERS, Mary; GUSE, Jan-hinrich; HAHN, Ulrike; STRASS, Simon; (0 pag.)WO2018/161039; (2018); A1;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion