Ferrocene, cas is 102-54-5, it is a common heterocyclic compound, the iron-catalyst compound, its synthesis route is as follows.
General procedure: A solution of acid chloride (63 mmol) in 30 mL drydichloromethane was added to a suspension of anhydrousaluminum chloride (8.41 g, 63 mmol) in 30 mLdry dichloromethane, and the mixture was stirred at 5 Cfor 1 h under Argon. The solution of aluminum chloride/acid chloride complex was added dropwise over 30 minto a solution of ferrocene (11.16 g, 60 mmol) in 100 mLdry dichloromethane at 0 C. The reaction mixture waswarmed to room temperature and stirred for 16 h. A solutionof NaBH4(2.38 g, 63 mmol) in 25 mL diglyme wasadded dropwise to the purple reaction mixture at -5 C. Anorange solution was formed and stirred at 0 C for 1 h. Themixture was then hydrolyzed with addition of 20 mL waterwhile maintaining its temperature at less than or equal to10 C. The mixture was allowed to separate by settling,and the organic phase was then withdrawn. The aqueousphase was extracted with 3 times 30 mL of dichloromethane,and then all the organic phases are combined. Combinedorganic layer was washed with 50 mL of brine. Afterthe drying of organic layer on the Na2SO4,dichloromethanewas distilled under atmospheric pressure. The diglymeand the residual ferrocene which was found to be entrainedby the diglyme were then distilled at reduced pressureapproximately 20 mm Hg and a column head temperatureof 85-95 C. The alkylferrocene derivatives were distilledat a more reduced pressure, less than 5 mm Hg., 102-54-5
As the rapid development of chemical substances, we look forward to future research findings about 102-54-5
Reference£º
Article; Teimuri-mofrad, Reza; Safa, Kazem D.; Abedinpour, Saiedeh; Rahimpour, Keshvar; Journal of the Iranian Chemical Society; vol. 14; 10; (2017); p. 2177 – 2185;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion