As a common heterocyclic compound, it belongs to iron-catalyst compound, name is Ferrocene, and cas is 102-54-5, its synthesis route is as follows.,102-54-5
Synthesis of ferrocenecarboxaldehyde (2) In a Schlenk-type apparatus, 2.1 mL (28 mmol) of DMF was added to the solution of 5.31 g (28 mmol) of ferrocene in 30 mL of dry chloroform, and the resulting mixture was stirred in an ice-bath under nitrogen atmosphere for 15 min. Then, 2.6 mL (28 mmol) of POCl3 was dropwise added to the mixture about half an hour. The resulting reaction mixture was refluxed for 12 h. After solvent removal, the product was poured into 100 mL ice water and filtered. The filtrate was neutralized with Na2CO3 power, and extracted repeatedly with ether. The crude product was obtained by evaporation of the solvent and purified by silica gel (100-200 mesh) chromatography to give a reddish-brown solid. Yield: 3.21 g, 53%. M.p. 123-124 C. 1H NMR (400 MHz, CDCl3): delta 9.99 (s, 1H, CHO), 4.82 (s, 2H, Cp-H), 4.63 (s, 2H, Cp-H), 4.30 (s, 5H, Cp-H). 13C NMR (101 MHz, CDCl3): delta 193.50 (CHO), 79.63 (Cp), 73.19 (Cp), 69.58 (Cp). MS (ESI) m/z 214.89 [M + H]+ Cal. 214.
With the complex challenges of chemical substances, we look forward to future research findings about 102-54-5,belong iron-catalyst compound
Reference£º
Article; Su, Zhi-Ming; Lin, Cai-Xia; Zhou, Yun-Tao; Xie, Li-Li; Yuan, Yao-Feng; Journal of Organometallic Chemistry; vol. 788; (2015); p. 17 – 26;,
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