1271-51-8, Vinylferrocene is a iron-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: A mixture of 4-bromo-7-(piperidin-1-yl)benzo[c][1,2,5]thiadiazole (2a) (0.298 g, 1 mmol), 4-vinylpyridine (0.115 g, 1.1 mmol), Pd(OAc)2 (5.0 mg, 0.022 mmol), NaOAc (0.82 g, 10 mmol), n-Bu4NBr (0.065 g, 0.2 mmol) and N,N-dimethylformamide (10 mL) was heated at 100 ¡ãC for 24 h under nitrogen atmosphere. After cooling, the reaction was quenched by adding excess water. The precipitate formed was filtered, washed with water, dissolved in dichloromethane, and dried over anhydrous sodium sulfate. After evaporation of the volatiles, the residue was purified by column chromatography on silica gel, using a hexanes/dichloromethane mixture (2:3) as eluant to obtain the title compound 3a. 4.2.6 4-((E)-2-Ferocenylvinyl)-7-((E)-2-(pyridin-4-yl)vinyl)benzo[c][1,2,5]thiadiazole (6c) Compound 6c (0.277 g, 73percent) was prepared as dark solid by following a procedure similar to that described above for 6a by using vinylferrocene. Rf (70percent CH2Cl2/hexanes) 0.39; mp 184-186 ¡ãC; numax (KBr film) 2924, 2847, 1622, 1380, 1100, 965, 810 cm-1; deltaH (500.13 MHz, CDCl3) 4.19 (5H, s, Cp), 4.40 (2H, s, Cp), 4.62 (2H, s, Cp), 7.22 (1H, s), 7.50 (2H, s), 7.61 (1H, buried d, vinyl), 7.69 (1H, d, J=6.0 Hz), 7.75 (1H, d, J=16.0 Hz, vinyl), 7.84 (1H, d, J=16.0 Hz, vinyl), 7.99 (1H, d, J=16.0 Hz, vinyl), 8.6 (2H, br s, pyridine); deltaC (125.77 MHz, CDCl3) 67.5, 69.5, 69.9, 83.0, 121.0, 121.5, 125.2, 126.8, 129.1, 129.2, 129.8, 131.2, 134.0, 145.0, 150.2, 153.7, 153.9; HRMS (ESI): MH+, found 449.0625. C25H19FeN3S requires 449.0649.
1271-51-8, 1271-51-8 Vinylferrocene 16211828, airon-catalyst compound, is more and more widely used in various fields.
Reference£º
Article; Prasad Bolisetty; Li, Chun-Ting; Thomas Justin; Bodedla, Govardhana Babu; Ho, Kuo-Chuan; Tetrahedron; vol. 71; 24; (2015); p. 4203 – 4212;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
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