Day: October 12, 2020

1271-51-8, Vinylferrocene is a iron-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: A deoxygenated mixture of vinylferrocene (170mg, 0.80mmol), K2CO3 (1.50g, 11mmol), tetrabutylammonium bromide (1.19g, 3.70mmol), bromochromone (0.66mmol) and Pd(OAc)2 (20mg, 0.09mmol) in DMF (23ml) was heated at 95¡ãC for 19h. After cooling to r. t. the reaction mixture was evaporated to dryness. Solid residue was dissolved in chloroform and extracted several times with water. The organic phase was dried with MgSO4, filtered and the solvent was removed from the filtrate in vacuo. The residue was subjected to chromatography on SiO2 (eluent: CHCl3/methanol, 50:2). Finally the analytically pure products were obtained after recrystallization from chloroform/n-hexane mixture.

1271-51-8, As the paragraph descriping shows that 1271-51-8 is playing an increasingly important role.

Reference£º
Article; Kowalski, Konrad; Koceva-Chy, Aneta; Szczupak, Lukasz; Hikisz, Pawel; Bernasin?ska, Joanna; Rajnisz, Aleksandra; Solecka, Jolanta; Therrien, Bruno; Journal of Organometallic Chemistry; vol. 741-742; 1; (2013); p. 153 – 161;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1271-51-8,Vinylferrocene,as a common compound, the synthetic route is as follows.

A mixture of vinylferrocene (1 mmol), K2CO3 (2.5or 5 mmol), tetrabutylammonium tetrafluoroborat (2.5 or 5 mmol),the given amount of appropriate bromine-substituted compoundand catalytic amount of Pd(OAC)2 in 10 ml DMF was stirred at 80 ¡ãCunder argon atmosphere overnight. After the completion of thereaction, the cooled mixture was filtered, diluted with CH2Cl2(50 ml) and washed with H2O (3 x 50 ml). The organic phase was dried over Na2SO4, filtered and the solvent was removed under thereduce pressure. The crude products were purified by columnchromatography on silica gel with hexane/EtOAC as eluent. Specificdetails for each compound are given below. 4-(2-Ferrocenylvinyl)benzaldehyde (3): from 0.1 g (0.47mmol)vinyl ferrocene and 0.08 g (0.47 mmol) 4-bromobenzaldehyde,0.11 g (0.36 mmol) red shining crystals was obtained in 88percent yield:Rf 0.50 (Hexane: EtOAc 9:1); m.p. 150 ¡ãC, lit. [13] 150-151 ¡ãC; 1HNMR (400 MHz, CDCl3, 25 C): delta 9.97 (s, 1H, CHO), 7.83 (d, 2H,ArH), 7.56 (d. 2H, ArH), 7.07 (d, 3J (H,H) 16 Hz, 1H, CH), 6.72 (d, 3J(H,H) 16 Hz, 1H, CH), 4.50 (t, J 1.78 Hz, 2H, Cp), 4.35 (t,J 1.78 Hz, 2H, Cp), 4.15 (s, 5H, Cp) ppm; FT-IR (KBr, cm1): 3074,3062 (w), 2936, 2852 (w), 1685 (s), 1591, 1561 (w), 814 (w).

1271-51-8, 1271-51-8 Vinylferrocene 16211828, airon-catalyst compound, is more and more widely used in various fields.

Reference£º
Article; Teimuri-Mofrad, Reza; Rahimpour, Keshvar; Ghadari, Rahim; Journal of Organometallic Chemistry; vol. 846; (2017); p. 397 – 406;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

Iron(III) acetylacetonate, cas is 14024-18-1, it is a common heterocyclic compound, the iron-catalyst compound, its synthesis route is as follows.,14024-18-1

A typical procedure for preparation of oil-soluble magnetite nanoparticles is briefly described as follows: first, 20 mL of diethylene glycol, 0.70 g (2 mmol) of iron (III) acetylacetonate, and 1.06 mL (3 mmol) of oleic acid were mixed in a 50 mL Teflon-lined stainless autoclave while magnetically stirring. Then, the autoclave was put into oven, kept at 180C for 5 h. After cooled to room temperature naturally, 40 mL ethanol was added to yield a black precipitate. The black Fe3O4 precipitate was separated by centrifuging at 10,000 rpm for 20 min, and re-dispersed in 10 mL of hexane or dried at 60C under vacuum for 24 h. (The as-prepared product was donated as SO1.) The as-synthesized Fe3O4 colloid in hexane is hydrophobic and stable for nearly a year, while the dried Fe3O4 sample can be stable for several months. The synthesis of water-soluble magnetite nanoparticles was carried out only by reacting an iron precursor, iron (III) acetylacetonate (Fe(acac)3), in the polyol medium (diethylene glycol) without oleic acid under the same reaction conditions. After cooling down to room temperature, 40 mL of ethyl acetate was added to the reaction solution resulted in a black precipitation of magnetite nanoparticles which was then separated from the solution by centrifuging at 10,000 rpm for 20 min. After washed with ethyl acetate for three times, the precipitation was re-dispersed in polar solvents such as ethanol and water for further investigation. The Fe3O4 solid productions could also be obtained by drying the precipitation at 60C under vacuum for 24 h. (The as-prepared product was donated as SW1.)

With the rapid development of chemical substances, we look forward to future research findings about Iron(III) acetylacetonate

Reference£º
Article; Chen, Fenghua; Zhao, Taonan; Chen, Qingtao; Han, Lifeng; Fang, Shaoming; Chen, Zhijun; Materials Research Bulletin; vol. 48; 10; (2013); p. 4093 – 4099;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

Ferrocenecarboxylic acid, cas is 1271-42-7, it is a common heterocyclic compound, the iron-catalyst compound, its synthesis route is as follows.,1271-42-7

Under a nitrogen atmosphere, to a stirred solution of ferrocene carboxylic acid (1.20 g, 5.2 mmol) in freshly distillated dichloromethane (10 ml), was added dropwise oxalyl chloride (4 ml, 46.8 mmol), at 0 C. The resulting mixture was stirred at ambient temp. for 4 h, then the solvent was removed under reduce pressure. The solution was triturated with hot pentane, then the mixture was filtered, and the filtrate was concentrated under reduced pressure. The resulting residue was crystallized from pentane to give a red crystalline solid (1.25 g, 97%): mp 134 C. 1H-NMR (300 MHz, CDCl3): delta 4.36 (s, 5H, C5H5), 4.66 (s, 2H, C5H4), 4.94 (s, 2H, C5H4).

With the rapid development of chemical substances, we look forward to future research findings about Ferrocenecarboxylic acid

Reference£º
Review; Saied, Nadia Malek; Mejri, Najoua; El Aissi, Radhia; Benoist, Eric; Saidi, Mouldi; European Journal of Medicinal Chemistry; vol. 97; (2015); p. 280 – 288;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

Iron(III) acetylacetonate, cas is 14024-18-1, it is a common heterocyclic compound, the iron-catalyst compound, its synthesis route is as follows.,14024-18-1

Cobalt (II) acetylacetonate Co(acac)2 and Iron (III) acetylacetonateFe(acac)3 precursors weighted as 1:2M ratio was dissolved in 50 ml of de-ionized water. The aqua solution was kept warm at 40 C for few minutes and very few drops of inorganic chemical reagent was added dropwise and stirred for 30 min to mix the cations homogeneously throughout the solution. 1% of alkali solution was added dropwise to the aqua precursor solution for a better control of particle size, which acts as a precipitating agent as well as maintaining the pressure in the autoclave by lowering the equilibrium vapour tension of water. Finally,the precursors solution was continuously stirred for 30 min and transferred into 150 ml Teflon coated stainless steel autoclave. Then the autoclave was sealed and kept in the muffle furnace for heat treatmentat the optimised reaction temperature of 200 C for 6 h and allowed to cool down to room temperature. The obtained dark precipitation was filtered by Whatman filter paper and washed several times by de-ionized water and absolute ethanol. The precipitate was then dried at 80 C for 5 h in hot air oven and subsequently annealed at 700 and 800 C. The samples were named as S1 (as-prepared),S2 (annealed at 700 C), and S3 (annealed at 800 C).

With the rapid development of chemical substances, we look forward to future research findings about Iron(III) acetylacetonate

Reference£º
Article; Shyamaldas; Bououdina; Manoharan; Journal of Magnetism and Magnetic Materials; vol. 493; (2020);,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.14024-18-1,Iron(III) acetylacetonate,as a common compound, the synthetic route is as follows.

The synthesis of hybrid magnetite-gold nanoparticles with core-shell structure has been carried out referring to a protocol available in the literature [24] . Reagents. Iron (III) acetylacetonate (Fe (acac) 3, 99%), 1,2- hexadecanediol ( C14H29CH (OH) CH2 (OH) , 90%), oleylamine (OAM, C9H18=C9H17NH2 , 70%) , oleic acid (OA, C9H18=C8H15-COOH, 99%), diphenyl ether ( C12H10O, 99%) , gold chloride (Au(Cl) – 3 H20, 99%) and other solvents (hexane and ethanol) (Sigma Aldrich) . 0.355 g of Fe (acac) 3 have been mixed in 10 ml of diphenyl ether with 1 ml of oleic acid, 1 ml of oleylamine, under argon atmosphere and vigorous stirring. Successively, 1 , 2-hexadecanediol is added to the solution. The resulting solution is warmed up to 200 C and kept under reflux for 2 h. The amounts of the used reagents are reported in Table 1. Table 1 Diphenyl ether 10 g Once the solution has been taken to room temperature, the reaction mixture has been used without any separation. In a typical synthesis, to 5 ml of the reaction solution of Fe304 nanoparticles in diphenyl ether 0.415 g of Au (CI) 3 -3H20, 1.55 g of 1 , 2-hexadecanediol, 0.25 ml of oleic acid, 1.5 ml of oleylamine and 15 ml of diphenyl ether have been added. Under argon atmosphere and vigorous stirring this mixture is warmed up to 200 C and kept in such condition for 1.5 h. The amounts of the used reagents are reported in Table 2. Table 2 Once the reaction mixture has been cooled up to room temperature ethanol has been added. A material of dark color has been precipitated by means of a centrifuge (one cycle of 20 minutes at 10000 rpm) The precipitate has been washed with ethanol and redispersed in hexane in the presence of 75 mM oleic acid and oleylamine. The nanoparticles solution has shown a dark red color., 14024-18-1

The synthetic route of 14024-18-1 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; PADUANO, Luigi; D’ERRICO, Gerardino; MONTESARCHIO, Daniela; VITIELLO, Giuseppe; MANGIAPIA, Gaetano; LUCHINI, Alessandra; IRACE, Carlo; COLONNA, Alfredo; SANTAMARIA, Rita; WO2014/64574; (2014); A1;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

Ferrocenecarboxylic acid, cas is 1271-42-7, it is a common heterocyclic compound, the iron-catalyst compound, its synthesis route is as follows.,1271-42-7

Ferrocenecarbonyl chloride was prepared in a schlenk line system to ensure moisture free environment as reported before [21]. In a typical reaction, ferrocene carboxylic acid (10.3601 g, 45.0 mmol) was firstly dried under vacuum at 50 C for 30 min and then dissolved in 75.0 mL of freshly distilled DCM. After that, pyridine(7.20 mL, 90.36 mmol) was added to the previous solution followed by the dropwise addition of oxalyl chloride (7.75 mL, 90.36 mmol) at 25 C. The reaction mixture was stirred for 30 min first at 25 C and then refluxed for 5 h. The contents of the reaction flask were evaporated under vacuum and petroleum ether (80.0 mL) was added. The mixture was stirred for 2 h at 90 C at this stage. At last, the solvent was evaporated to get the dried ferrocene monocarbonyl chloride.

With the rapid development of chemical substances, we look forward to future research findings about Ferrocenecarboxylic acid

Reference£º
Article; Khan, Amin; Wang, Li; Yu, Haojie; Haroon, Muhammad; Ullah, Raja Summe; Nazir, Ahsan; Elshaarani, Tarig; Usman, Muhammad; Fahad, Shah; Naveed, Kaleem-ur-Rehman; Journal of Organometallic Chemistry; vol. 880; (2019); p. 124 – 133;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

Acetylferrocene, cas is 1271-55-2, it is a common heterocyclic compound, the iron-catalyst compound, its synthesis route is as follows.,1271-55-2

General procedure: To a magnetic stirred solution of acylferrocene (10 mmol) in methanol (30 mL) tosylhydrazine (10 mmol) was added. Then the mixture was stirred vigorously at 70 C. TLC analysis was performed until the spot of acylferrocene disappeared. Then the solution was cooled to room temperature, and N-tosylhydrazone precipitated. The precipitate was filtered and washed with petroleum ether (10 mL * 2) to get the pure product.

With the rapid development of chemical substances, we look forward to future research findings about Acetylferrocene

Reference£º
Article; Liu, Yueqiang; Ma, Xiaowei; Liu, Yan; Liu, Ping; Dai, Bin; Synthetic Communications; vol. 48; 8; (2018); p. 921 – 928;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

1273-86-5, Ferrocenemethanol is a iron-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: To a mixture of 1.0 mmol of ferrocenylcarbinol and 1.0 mmol of the corresponding heterocycle in 1.0 ml of methylene dichloride, 0.18 ml of 45 % aqueous solution of fluoroboric acid was added under vigorous stirring. The agitation was continued for 5 min then Et2O (15 ml), the same amount of cold water, and 5-10 mg of ascorbic acid were added to the reaction flask. After vigorous shaking of the mixture the organic solution was separated, washed with cold water (3¡Á15 ml), the solvent was removed and the residue was dried over CaCl2. All types of products (pyrrolidine as well as imidazolidine and thiazolidine derivatives) were equally purified, namely by column chromatography (silica, eluent hexane EtOAc 3:1), and solids obtained after chromatography were crystalized from ethanol.1-(1-Ferrocenylmethyl)pyrrolidine-2-thione (5). (85%); orange powder; mp 104.8 – 105.6o. 1H NMR (400 MHz, CDCl3) delta (ppm): 2.02 (m, 2, 2), 2.61 (m, 2, 2), 3.90 (m, 2, 2), 4.12 (s, 2H, Fc), 4.14 (s, 2, 2), 4.13 (s, 5H, Fc), 4.25 (s, 2H, Fc). 13C NMR (100 MHz, CDCl3) delta (ppm): 19.8 (CH2), 45.2 (CH2), 49.3 (CH2), 52.1 (CH), 66.0 (C5H4), 67.6 (C5H4), 68.8 (C5H4), 68.9 (C5H4), 69.1 (C5H5), 86.9 (ipso-C5H4), 200.1 (C=S) Calc. for C15H17FeNS: 61.22; H, 5.74; N, 4.69; Fe, 18.67; S, 10.72. Found: C, 60.21; H, 5.73; Fe, 18.66; N, 4.68; S, 10.72. EI/MS, m/z (RI%): 299 [M]+ (46).

1273-86-5, As the paragraph descriping shows that 1273-86-5 is playing an increasingly important role.

Reference£º
Article; Rogatkina, Elena Yu.; Ivanova, Anna S.; Rodionov, Alexey N.; Peregudov, Alexander S.; Korlyukov, Alexander A.; Volodin, Alexander D.; Belousov, Yury A.; Simenel, Alexander A.; Arkivoc; vol. 2018; 5; (2018); p. 272 – 282;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

1271-51-8, Vinylferrocene is a iron-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Ethynylferrocene (1) (0.5 g, 2.380 mmol) was dissolved in dryethanol (35 mL) and cooled to 0 ¡ãC and subsequently treated withsolid KOH (0.340 g, 6 mmol). After 30 min of stirring at a lowtemperature solid N-iodosuccinimide (0.642 g, 2.856 mmol) wasadded to the mixture, and the stirring continued at 0 ¡ãC for additional30 min. The cold bath was then removed and the stirringcontinued at room tempreture for an additional 2 h. Aftercompletion of reaction (monitored by TLC) 100 mL of EtOAc wasadded and the mixture extracted three times with brine. Theorganic layer was separated, dried over Na2SO4, filtered, andevaporated. The productwas isolated in quantitative yield as brownSolid.Yield: 94percent (brown solid); m.p 112-115 ¡ãC (lit. 116-117 C) [47];1H NMR (500 MHz, CDCl3): delta 4.18-4.23 (m, 7H), 4.44-4.47 (m,2H) ppm; 13C NMR (75 MHz, CDCl3): delta 66.4, 69.4, 69.5, 70.6, 70.7,70.77, 70.84, 70.9, 72.5, 74.3, 92.8 ppm., 1271-51-8

The synthetic route of 1271-51-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Yousuf, Md; Mukherjee, Debarati; Dey, Somaditya; Pal, Chiranjib; Adhikari, Susanta; European Journal of Medicinal Chemistry; vol. 124; (2016); p. 468 – 479;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion