Ferrocenemethanol, cas is 1273-86-5, it is a common heterocyclic compound, the iron-catalyst compound, its synthesis route is as follows.,1273-86-5
General procedure: Amine (1.0mmol), In(OTf)3 (0.1mmol) and anisyl alcohol (1.2mmol) were added into a flask. Then the mixture was vigorously stirred at reflux, until amine was completely consumed as indicated by TLC analysis or 24h. After the completion of reaction, CH2Cl2 (15mL¡Á2) was used to extract the product, the organic layer was dried with anhydrous Na2SO4. Then the solvent was evaporated under the reduced pressure. The residue was purified by flash column chromatography with ethyl acetate and petroleum ether as eluents to afford pure product. This procedure was followed for the synthesis of other N-benzylation amines.
As the rapid development of chemical substances, we look forward to future research findings about 1273-86-5
Reference£º
Article; Yang, Jin-Ming; Jiang, Ran; Wu, Lin; Xu, Xiao-Ping; Wang, Shun-Yi; Ji, Shun-Jun; Tetrahedron; vol. 69; 37; (2013); p. 7988 – 7994;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion