As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO163,mainly used in chemical industry, its synthesis route is as follows.,1271-55-2
To a 100 mL round bottom reaction flask was added p-toluenesulfonyl hydrazide (1.5 eq)Methanol was gradually added until the p-toluenesulfonyl hydrazide was completely dissolved.Heated to 60oC,After a small amount of methanol was used to dissolve acetyl ferrocene (1 equivalent) prepared in the previous reaction,Was added dropwise to p-toluenesulfonyl hydrazide solution,Stirring to reflux to a large amount of solid precipitation.Suction filtered, washed with petroleum ether,Dry, getAcetylferrocene p-toluenesulfonyl hydrazone.Yield 81%.
With the complex challenges of chemical substances, we look forward to future research findings about Acetylferrocene,belong iron-catalyst compound
Reference£º
Patent; Inner Mongolia University; Zhang Hao; Ling Li; Hu Jianfeng; Huo Yanhong; (11 pag.)CN107226829; (2017); A;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion