Day: October 27, 2020

1273-86-5, Ferrocenemethanol is a iron-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

(3) Chlorinated ferrocene methane synthesis: under the protection of the helium, the ferrocene methanol (250 mg, 1 . 16 mmol) dissolved into dichloromethane (20 ml) in, then the oxalyl (6 drops, excess) into the wherein after then completing, in helium under the protection of the stirring 4 h, after the reaction, the solvent is removed by reduced pressure distillation, for fixing the residue water (10 ml) flushing.(4) Containing ferrocene group of the carbamate compound synthesis: amount taking 0. 6 Ml (1.0 mmol) is dissolved in carbon disulfide and 5 ml of ethanol, measuring the 2.4 g (1.0 mmol) di-n-octyl amine and 1.4 ml (i. the 0 1.0 mmol) triethylamine are added 1 a 50 ml three flasks; under the condition of the ice slowly dripping into carbon bisulfide ethanol solution, stirring 1 h; the removal of the ice bath, in the continuing stirring at room temperature 2 h; then adding 0.25 g (1.0 mmol) chloro ferrocene methane ethanol solution of 10 ml, to control the temperature 5 C following reaction 1 h, then raising the stirring to reflux 2 h; TLC monitoring the reaction, solvent system as developing solvent (benzene and acetone of volume ratio of 1:1); boil off ethanol, adding anhydrous ethyl ether 20 ml, filtering out the deposit, the filtrate water washing 3 times, then the molecular sieve drying, filtering, the steamed ethyl ether to obtain yellow solid, yield 82. 8%, Melting point 100 – 102 C.

1273-86-5, The synthetic route of 1273-86-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Shandong Yuangen Petrochemical Co., Ltd.; Qiao Liang; Yuan Junzhou; Song Laigong; He Jingsong; Liu Shanshan; (7 pag.)CN104710482; (2018); B;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

Name is Ferrocenemethanol, as a common heterocyclic compound, it belongs to iron-catalyst compound, and cas is 1273-86-5, its synthesis route is as follows.,1273-86-5

General procedure: To a solution of ferrocenyl alcohol 1 or 2 (2.0 mmol) and correspondingmercapto derivative in dry MeNO2 (5 mL) CAN (22 mg,0.04 mmol, 0.2 mol%) was added. The resulting mixture was stirredat room temperature until TLC analysis revealed complete disappearanceof starting alcohol 1 or 2 (usually 3-4 h). Then reactionmixture was poured onto a water (40 mL), organic layer was separated,the aqueous phase was extracted with EtOAc (2 10 mL),and the combined organic solution was dried over Na2SO4, filteredand the solvents were evaporated in vacuo. The remained productwas treated with CH2Cl2 (50 ml) and passed through a silica gellayer (2.5 cm) on the filter to give corresponding products 5-9,11 after the evaporation of volatiles at reduced pressure.

With the complex challenges of chemical substances, we look forward to future research findings about Ferrocenemethanol

Reference£º
Article; Ol’shevskaya, Valentina A.; Makarenkov, Anton V.; Borisov, Yury A.; Ananyev, Ivan V.; Kononova, Elena G.; Kalinin, Valery N.; Ponomaryov, Andrey B.; Polyhedron; vol. 141; (2018); p. 181 – 190;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

Ferrocenecarboxylic acid, cas is 1271-42-7, it is a common heterocyclic compound, the iron-catalyst compound, its synthesis route is as follows.,1271-42-7

Ferrocenecarboxylic acid (303 mg, 1.32 mmol) and N-hydroxysuccinimide (170 mg, 1.47 mmol) were dissolved in dioxane (15 ml) and added with stirring to a solution of dicyclohexylcarbodiimide (305 mg, 1.48 mmol) in dioxane (3 ml). The mixture was stirred at room temperature for 24 hours during which time a precipitate was formed. The precipitate was removed by filtration, solvent was removed from the filtrate in vacuo and the resulting solid purified by silica gel column chromatography, eluting with 8:2 petrol:ethyl acetate. Yield 320 mg, 74%.

As the rapid development of chemical substances, we look forward to future research findings about 1271-42-7

Reference£º
Patent; Atlas Genetics Limited; Braven, Helen; Keay, Russell; (59 pag.)US2016/25703; (2016); A1;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

Name is Ferrocenecarboxylic acid, as a common heterocyclic compound, it belongs to iron-catalyst compound, and cas is 1271-42-7, its synthesis route is as follows.,1271-42-7

2-(4-Ferrocenylbenzamido)benzamide (50k). Ferrocenecarboxylic acid (1.00 g, 4.4 mmol) was treated with oxalyl chloride (3.87 g, 30.5 mmol) in dry dichloromethane (20 ml_) under argon for 4 h. The solvent and excess reagent were evaporated. The residue was extracted with hexane (30 ml_). The suspension was filtered and the solvent was evaporated from the filtrate to give crude ferrocenecarbonyl chloride (820 mg) as a red oil. This material, in dry tetrahydrofuran (20 ml_), was added to 2-amino- benzamide 49 (410 mg, 3.0 mmol), dry pyridine (316 mg, 4.0 mmol) and 4-dimethyl- aminopyridine (82 mg, 0.7 mmol in dry tetrahydrofuran (20 ml_). The mixture was stirred for 16 h under argon. The solvent was evaporated. Chromatography (ethyl acetate / petroleum ether 3:2) gave 2-(4-ferrocenylbenzamido)benzamide 50k (980 mg, 98%) as a red oil; 1H NMR ((CD3)2SO) delta 4.24 (5 H, s, Cp2-H5), 4.49 (2 H, m, Cp^ 3,4- H2), 4.78 (2 H, m, C ^ 2,5-H2), 7.1 1 (1 H, t, J = 7.5 Hz, 5-H), 7.51 (1 H, t, J = 7.5 Hz, 4- H), 7.82 (1 H, s, CONHH), 7.85 (1 H, d, J = 7.5 Hz, 6-H), 8.35 (1 H, s, CONHH), 8.57 (1 H, d, J = 7.5 Hz, 3-H); 13C NMR ((CD)3SO) (HSQC / HMBC) delta 68.07 (C ^ 2,5-C2), 69.56 (Cp2-C5), 70.77 (Cp FontWeight=”Bold” FontSize=”10″ 3,4-C2), 76.58 (Cp 1-C), 1 18.49 (1-C), 1 19.63 (3-C), 121.73 (5-C), 128.58 (6-C), 132.35 (4-C), 140.23 (2-C), 168.13 (NHCO), 171.13 (CONH2); MS m/z 371.0468 (M + Na)+ (C18H1656FeN2Na02 requires 371.0459).

With the complex challenges of chemical substances, we look forward to future research findings about Ferrocenecarboxylic acid

Reference£º
Patent; UNIVERSITY OF BATH; THREADGILL, Michael David; LLOYD, Matthew David; THOMPSON, Andrew Spencer; NATHUBHAI, Amit; WOOD, Pauline Joy; PAINE, Helen Angharad; KUMPAN, Ekaterina; SUNDERLAND, Peter Thomas; CHUE YEN WOON, Esther; WO2014/87165; (2014); A1;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

14024-18-1, Iron(III) acetylacetonate is a iron-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

The synthesis of Fe3O4 NPs refers to the previousmethod.19 18 1,2-hexadecanediol (10 mM), Fe(acac)3(2 mM), oleicacid (6 mM) and oleylamine (6 mM) wereadded into 20 mL of diphenyl ether, and stirred vigorouslyunder the protection of nitrogen. The mixture wereheated at 473 K for 45 min, then refluxed under the protectionof nitrogen at 538 K for 120 min to prepare thegrey-black mixture. After cooled down to the room temperature,60 mL of ethanol was added, the raw productswere collected by centrifugation, and then dispersed into10 mL of n-hexane. The ethanol (60 mL) was added, followedby centrifugation, and the procedure was repeatedfor 8-10 times in order to clean thoroughly. Finally, the5-nm Fe3O4 nanoparticles were synthesized and preservedin n-hexane.

14024-18-1, The synthetic route of 14024-18-1 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Gan, Qi; Zhu, Jiaoyang; Yuan, Yuan; Liu, Changsheng; Journal of Nanoscience and Nanotechnology; vol. 16; 6; (2016); p. 5470 – 5479;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

Name is Iron(III) acetylacetonate, as a common heterocyclic compound, it belongs to iron-catalyst compound, and cas is 14024-18-1, its synthesis route is as follows.,14024-18-1

In a 100 mL Schlenk tube 1.00 g (2.83 mmol) of Iron(III)-acetylacetonate (Fe(AcAc)3), synthesized as reported in Bondioliet al., [13] was dissolved in different amounts of BzOH in order to evaluate the effect of the Fe(AcAc)3:BzOH ratio on the powder properties (see composition details in Table 1). The reaction was left stirring at room temperature for 15 min and then heated to 200C in an oil bath for 48 h. The main reaction occurring in the solvothermal treatment of Iron(III)-acetylacetonate in benzyl alcoholis summarized in the scheme of Fig. 1. After reaction a stable suspension was obtained. To better characterize the inorganic phase, the obtained powders were dispersed in methanol with an ultrasonic bath and centrifuged at 4000 rpm for 60 min; the powders were washed, centrifuged till the obtainment of a colourless liquid phase and finally dried under reduced pressure.

With the complex challenges of chemical substances, we look forward to future research findings about Iron(III) acetylacetonate

Reference£º
Article; Sciancalepore, Corrado; Bondioli, Federica; Messori, Massimo; Barrera, Gabriele; Tiberto, Paola; Allia, Paolo; Polymer; vol. 59; (2015); p. 278 – 289;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1271-42-7,Ferrocenecarboxylic acid,as a common compound, the synthetic route is as follows.

Ferrocenecarboxylic acid (303 mg, 1.32 mmol) and N-hydroxysuccinimide (170 mg, 1.47 mmol) were dissolved in dioxane (15 ml) and added with stirring to a solution of dicyclohexylcarbodiimide (305 mg, 1.48 mmol) in dioxane (3 ml). The mixture was stirred at room temperature for 24 hours during which time a precipitate was formed. The precipitate was removed by filtration, solvent was removed from the filtrate in vacuo and the resulting solid purified by silica gel column chromatography, eluting with 8:2 petrol:ethyl acetate. Yield 320 mg, 74%.

1271-42-7, The synthetic route of 1271-42-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Atlas Genetics Limited; Braven, Helen; Keay, Russell; (59 pag.)US2016/25703; (2016); A1;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

Ferrocenemethanol, cas is 1273-86-5, it is a common heterocyclic compound, the iron-catalyst compound, its synthesis route is as follows.,1273-86-5

The benzonitrile (103mg, 1mmol), [(IPr) AuNTf] (17mg, 0.02mmol, 2mol%),tetrahydrofuran (0.5ml), H 2O (0.5ml) were successively added to the reaction flask25mlSchlenk. After the mixture was reacted at 130 C at 12 hours, cooled to roomtemperature, the solvent was removed in vacuo under reduced pressure. The [Cp * IrCl 2]2(8mg, 0.01mmol, 1mol%), ferrocene methanol (260mg, 1.2mmol), cesium carbonate (65mg,0.2equiv.) And toluene (1ml) was added to the reaction flask and the reaction mixturewas continued at 130 C at 12 hours, cooled to room temperature. The solvent was removedrotary evaporation, then purified by column chromatography (developing solvent: ethylacetate / petroleum ether) to give pure title compound Yield: 83%.

With the synthetic route has been constantly updated, we look forward to future research findings about Ferrocenemethanol,belong iron-catalyst compound

Reference£º
Patent; Nanjing University of Science and Technology; Ma, Juan; Wang, Na Na; Li, Feng; (16 pag.)CN105820061; (2016); A;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

1271-55-2, Acetylferrocene is a iron-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a 500 mL three-necked flask equipped with a mechanical stirrer and a spherical condenser were added 0.01 mol of acetyl ferrocene,0.1 mol morpholine,0.05 mol of sulfur and 0.001 mol of Na2S ¡¤ 9H2O, Oil bath was heated to 128 deg C, Reflux 7h, TLC monitoring.The reaction is completed,The mixture was cooled to room temperature,Then, 10 mL of ethanol and 25 mL of 2 mol / L sodium hydroxide aqueous solution were added thereto,Stirring temperature,Reflux 4h,TLC monitoring.The reaction is completed,cool down,Adjust the pH value with hydrochloric acid to between 7 and 8,Filter cleaning,The filtrate was then adjusted to pH 1 with hydrochloric acid,Placed overnight,filter,Washed,A yellow-brown solid,Namely ferrocenyl acetic acid,The yield is 79%.

1271-55-2, As the paragraph descriping shows that 1271-55-2 is playing an increasingly important role.

Reference£º
Patent; Shaanxi University of Science and Technology; Liu, Yuting; Song, Simeng; Yin, Dawei; Jiang, Shanshan; Liu, Beibei; Yang, Aning; Wang, Jinyu; Lyu, Bo; (13 pag.)CN104231004; (2017); B;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1273-86-5,Ferrocenemethanol,as a common compound, the synthetic route is as follows.

The cyanuric chloride (TCT)(0.184 g, 1 mmol) and 30 mL of dry tetrahydrofuran were added to a 100 mL round bottom flask,To a stirred solution of 20 mL of ferrocene methanol (0.864 g, 4 mmol) Of the dry tetrahydrofuran solution was slowly added dropwise to the reaction system.After stirring for 30 minutes under ice bath, 10 mL of a solution containing DMAP (0.366 g, 3 mmol)In a dry tetrahydrofuran solution was slowly added dropwise to the reaction system, and the mixture was stirred at room temperature for 5 minutes after stirring for 30 minutes. After the reaction was carried out at room temperature for 5 to 6 hours, the reaction was refluxed. After completion of the reaction, the reaction solution was concentrated under reduced pressure,The residue was separated by column chromatography using (V petroleum ether: V ethyl acetate, 5: 1-2: 1)The mobile phase was eluted to give nitroxyl radical containing ferrocene derivative I, 0.506 g, yield: 70%.

1273-86-5, 1273-86-5 Ferrocenemethanol 10856885, airon-catalyst compound, is more and more widely used in various fields.

Reference£º
Patent; Xiamen Xitu Materials Institute; Yong Jianping; Lu Canzhong; (9 pag.)CN104804047; (2017); B;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion