1271-55-2, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Acetylferrocene, cas is 1271-55-2,the iron-catalyst compound, it is a common compound, a new synthetic route is introduced below.
A solution of pure TsNHNH2 (15 mmol) in methanol (30 mL) was stirred and heated to 60 C until the TsNHNH2 dissolved. The mixture was cooled to room temperature. Then a solution of acetyl ferrocene 1a (10 mmol) in methanol was dropped into the mixture slowly. After approximately 0.5 h, the crude products could be obtained as solid precipitate. The precipitate was washed with petroleum ether then removed in vacuo to give yellow solid 2a in 86 % yield. mp 187-189 C. 1H NMR (500 MHz, DMSO) delta 10.00 (s,1H), 7.81 (d, J = 7.9 Hz, 2H), 7.43 (d, J = 7.8 Hz, 2H), 4.49 (s, 2H), 4.29 (s, 2H), 3.93 (s, 5H), 2.36 (s, 3H), 2.04 (s, 3H). 13C NMR (126 MHz, DMSO) d 155.1, 143.0, 136.4, 129.1, 127.6, 69.6, 68.9, 66.8, 20.9, 15.0. HRMS (ESI-TOF) m/z: [M]+ calcd. for C19H20FeN2O2S 396.0595; Found: 396.0594.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Acetylferrocene, 1271-55-2
Reference£º
Article; Ling, Li; Hu, Jianfeng; Zhang, Hao; Tetrahedron; vol. 75; 17; (2019); p. 2472 – 2481;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
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