12093-10-6, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Ferrocenecarboxaldehyde, cas is 12093-10-6,the iron-catalyst compound, it is a common compound, a new synthetic route is introduced below.
Ferrocene carboxyl aldehyde (0.100 g, 0.467 mmol) was dissolved in ethanol (8 mL), was added slowly in small portions sodium borohydride (0.090 g, 2.4mmol) at 0 . The reaction mixture was stirred at ambient temperature for 3 hours. It was add water (3mL) and dichloromethane (10 mL) in turn to complete the reaction.The organic layer was separated and the remaining water layer was extracted three times with dichloromethane (15mL x 3). The combined organic layer is washed with a saturated aqueous sodium chloride solution, placed into the over anhydrous sodium sulfate, filtered under reduced pressure. After removal of all the solvent in the filtrate under reduced pressure was purified by column chromatography (hexane: ethyl acetate: methanol = 15: 5: 1) to give the compound 2a to give a yellow solid. (0.090 g, 89%)
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Ferrocenecarboxaldehyde, 12093-10-6
Reference£º
Patent; Diatech Korea Co. Ltd.; Sogang University Research Foundation; Moon, PongJin; Oh, HaNa; Kang, NaNa; Cheon, AeRan; Park, Gye Shin; Park, Hyeong Soon; Pang, Choo Young; (31 pag.)KR101583811; (2016); B1;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion