Introduction of a new synthetic route about 102-54-5

102-54-5, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,102-54-5 ,Ferrocene, other downstream synthetic routes, hurry up and to see

As a common heterocyclic compound, it belongs to iron-catalyst compound, name is Ferrocene, and cas is 102-54-5, its synthesis route is as follows.

A mixture of 5.3g (28mmol) ferrocene and 60mL chloroform was placed in a 50mL three-neck flask and kept at-5 to-10C. Afterward, 10.5mL phosphorus oxychloride dissolved in 15mL DMF was added for 1.5h. The resulting reaction mixture was refluxed for 12h. After solvent removal, the product was poured into 100mL ice water and filtered. The filtrate was neutralized to pH 8-9 using NaOH (10%, w/v) and then extracted with ether. The organic layer was washed with water and dried over anhydrous MgSO4. After removal of the solvent, the crimson solid was recrystallized from n-hexane. The purified product (1) weighed 2.3g (79% yield). 1H NMR(CDCl3): delta, 9.95 (s, 1H, HC=O), 4.79-4.80 (d, 2H, Cp-rings), 4.60-4.61(d, 2H, Cp-rings), 4.28(s, 5H, Cp?-rings). MS(ESI), m/z: 215.0 (M+) FT-IR (KBr): upsilon (cm-1) 1681(C=O).

102-54-5, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,102-54-5 ,Ferrocene, other downstream synthetic routes, hurry up and to see

Reference£º
Article; Jia, Jianhong; Cui, Yanhong; Li, Yujin; Sheng, Weijian; Han, Liang; Gao, Jianrong; Dyes and Pigments; vol. 98; 2; (2013); p. 273 – 279;,
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