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A method of cyclic amine alpha – catalysed synthesis (by machine translation)

The invention discloses a method for synthesizing alpha – cyclic amine method, which comprises the following steps: in the reaction container, joins the alkone, the compound is mellow, iridium complex catalyst, tertiary amyl alcohol base and a solvent, the reaction mixture in the air reflux reaction, after the reaction to cool to room temperature, the solvent is removed by rotary evaporation, then through the column separation, to obtain the target compound. The invention uses an N? C? N ligand complex three tooth iridium, reaction only need to add 0.2 equivalent of carbonate, in the air, reaction only needs 10 – 12 hours, demonstrating the obvious advantages; therefore, the reaction in accordance with the requirement of green chemistry, has broad prospects of development. (by machine translation)

A method of cyclic amine alpha – catalysed synthesis (by machine translation)

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Recommanded Product: 1273-86-5, you can also check out more blogs about1273-86-5

Reference£º
Iron Catalysis in Organic Synthesis | Chemical Reviews,
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion