Synthetic Route of 1271-48-3, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.1271-48-3, Name is 1,1′-Ferrocenedicarboxaldehyde, molecular formula is C12H10FeO2. In a article£¬once mentioned of 1271-48-3
Synthesis of controlled pi-extended conjugate nanostructures of 1,1?-ferrocene
Synthesis of the (E,E)-1,1?-ferrocene nanostructures having controlled pi-extended conjugation was satisfactory carried out starting of 1?-[2-(1,3-dioxolan)]-1-formylferrocene (1). The molecular unit (E)-1?-[2-(1,3-dioxolan)]-1-[beta-(p-iodophenyl)ethenyl]ferrocene (2), was obtained in excellent yield by treatment of 1 with p-iodobenzyl triphenylphosphonium ylid followed by Z?E isomerization, catalyzed by iodine, in quantitative yield. Compound (E)-2 was transformed in (E)-1?-{2-(1,3-dioxolan)-1-[beta-[4-(3-hydroxy-3-methyl-but-1-ynyl)-phenyl]-ethenyl}ferrocene, (E)-4, by palladium catalyzed cross-coupling with 2-methyl-but-3-yn-2-ol. (E)-4 gives (E)-1-[beta-(4-ethynylphenyl)-ethenyl]-1?-[2-(1,3-dioxolan)]ferrocene (E)-5 by powder sodium hydroxide treatment. The molecular unit (E,E)-1-{beta-[4-(beta-(1?-formylferrocenyl)-ethenyl)-phenylethynyl]-phenyl]-ethenyl}-1?-formylferrocene, (E,E)-6, was synthesized by palladium catalyzed cross-coupling between the p-iodophenyl derivative (E)-2 and their ethynyl derivative (E)-5, in good yield. The (E,E)-1,1?-(p-iodophenyl)ethenyl ferrocene, (E,E)-7, was synthesized by reaction between 1,1?-diformylferrocene and the p-iodobenzyltriphenylphosphonium ylid, as a mixture of isomers which were purely isolated. Moreover, isomerization of the Z,Z and E,Z mixture to the E,E isomer, was induced by sunlight exposure, catalyzed by iodine, in quantitative yield. The (E,E)-1,1?-[beta-(4-ethynylphenyl)-ethenyl]ferrocene, (E,E)-10, was synthesized in good yield, by palladium catalyzed cross-coupling of compound (E,E)-7 with 2-methyl-but-3-yn-2-ol, followed by powder sodium hydroxide treatment.
Synthesis of controlled pi-extended conjugate nanostructures of 1,1?-ferrocene
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 1271-48-3
Reference£º
Iron Catalysis in Organic Synthesis | Chemical Reviews,
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion