Electric Literature of 1273-86-5, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 1273-86-5, Name is Ferrocenemethanol, molecular weight is 206.99. In an Article£¬once mentioned of 1273-86-5
Tuneable superbase-catalyzed vinylation of alpha-hydroxyalkylferrocenes with alkynes
Superbase-catalyzed (KOH/DMSO suspension as a catalyst) vinylation of hydroxymethyl- and hydroxyethylferrocenes with terminal and internal alkynes (acetylene, propyne, phenylacetylene, 3-ethynylpyridine, 1-propyn-1-yl-benzene, diphenylacetylene) affords hitherto unknown vinyl ethers of ferrocene in 30-93% yields depending on the alkyne structure and the tuneable ratio of reactants/KOH/DMSO. The vinylation smoothly proceeds under mild conditions (70-90 C, 0.25-13 h). With unsubstituted acetylene the process is readily realized under atmospheric pressure (yield of the corresponding vinyl ethers is 81-90%) though under pressure (initial pressure at room temperature is 10-13 atm, maximum pressure is 13-16 atm at the reaction temperature) the yield is close to quantitative (93%). The synthesized compounds were characterized using 1H and 13C NMR, and IR spectroscopy, as well as X-ray diffraction analysis.
Tuneable superbase-catalyzed vinylation of alpha-hydroxyalkylferrocenes with alkynes
Future efforts will undeniably focus on the diversification of the new catalytic transformations. We¡¯ll also look at important developments of the role of 1273-86-5, and how the biochemistry of the body works.Electric Literature of 1273-86-5
Reference£º
Iron Catalysis in Organic Synthesis | Chemical Reviews,
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion