Irreversible inhibitors are therefore the equivalent of poisons in heterogeneous catalysis. category: iron-catalyst, Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction by binding to a specific portion of an enzyme and thus slowing or preventing a reaction from occurring. In a patent，Which mentioned a new discovery about 1271-48-3
An Enantioselective Oxidative C-H/C-H Cross-Coupling Reaction: Highly Efficient Method to Prepare Planar Chiral Ferrocenes
A Pd-catalyzed, asymmetric oxidative cross-coupling reaction between ferrocenes and heteroarenes is described. The process, which takes place via a twofold C-H bond activation pathway, proceeds with modest to high efficiencies (36-86%) and high levels of regio- and enantioselectivity (95-99% ee). In the reaction, air oxygen serves as a green oxidant and excess amounts of the coupling partners are not required. The process is the first example of a catalytic asymmetric biaryl coupling reaction that occurs via double C-H bond activation. Finally, the generated coupling products can be readily transformed into chiral ligands and catalysts.
An Enantioselective Oxidative C-H/C-H Cross-Coupling Reaction: Highly Efficient Method to Prepare Planar Chiral Ferrocenes
If you are interested in 1271-48-3, you can contact me at any time and look forward to more communication. The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules. category: iron-catalyst
Reference：
Iron Catalysis in Organic Synthesis | Chemical Reviews,
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion