Reference of 1271-48-3, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In an article, 1271-48-3, molcular formula is C12H10FeO2, belongs to iron-catalyst compound, introducing its new discovery.
1,1?-Ferrocene biscarboxaldehyde (1) has been prepared and the aldehyde groups were subsequently protected with acetal groups to produce 1,1?-bisacetalferrocene (2). A ring-locked ferrocene was synthesised by further derivatisation of the cyclopentadiene rings at the 2,2? positions with phosphine substituents to produce 2,2?-bis-(acetal)-1,1?-diphenylphosphinoferrocene (3), which was subsequently coordinated to either a nickel chloride (5) or nickel bromide (6) metal centre. The ring-locked ferrocene complexes produced 2,5?-bis-(acetal)-1,1?-diphenylphosphinoferrocene substitution patterns. The acetal protecting groups of 2,2?-bis-(acetal)-1,1?-diphenylphosphinoferrocene were removed to produce 1,1?-bis-carboxaldehyde-2,2?-diphenylphosphinoferrocene (4). The Cp rings of 1,1?-bisacetalferrocene were also further derivatised at the 2,2? positions with a silane to produce the ring-locked 1,1?-siloxane-2,5?-bisacetalferrocenophane (7). The acetal protecting groups were removed from this to produce 1,1?-siloxane-2,5?-ferrocenophanecarboxaldehyde (8). For both the phosphine and siloxane electrophiles, the substitution on the Cp rings gives chiral products (obtained as racemic mixtures). Due to the highly regioselective nature of the reaction and diastereoselectivity in the products only C2-symmetric compounds were observed without the presence of meso diastereoisomers. Subsequent ring-locking forced the Cp rings to rotate, leading to 1,1?-ring-locked ferrocenes with 2,5?-arrangement of the acetal groups (i.e. on opposite faces of the ferrocene unit).
Future efforts will undeniably focus on the diversification of the new catalytic transformations. We’ll also look at important developments of the role of 1271-48-3, and how the biochemistry of the body works.Reference of 1271-48-3
Reference：
Iron Catalysis in Organic Synthesis | Chemical Reviews,
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion