1271-55-2, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Acetylferrocene, cas is 1271-55-2,the iron-catalyst compound, it is a common compound, a new synthetic route is introduced below.
General procedure: To a solution of acetyl ferrocene (228 mg, 1mmol) in ethyl alcohol (15 ml) was added KOH (110 mg, 2 mmol) and stirred at room temperature for 15 min, then appropriate aromatic aldehyde (1 mmol) in ethyl alcohol (5 ml) was slowly added and the mixture was allowed to stirred at room temperature. After complete consumption of acetyl ferrocene (monitored by TLC, a red to purple colour solid was formed), 2-hydrazinobenzothiazole (165 mg, 1.0 mmol), KOH (110 mg, 2 mmol) and additional ethyl alcohol (5 ml) and was slowly added and the resulting mixture was refluxed for overnight. After completion of the reaction (monitored by TLC, an orange to red colour solid was formed), the reaction mixture was cooled, the solid formed was filtered, washed with cold ethanol-water mixture, water and air dried. The resulting solid was purified by column chromatography using n-hexane/ethyl acetate mixture (9:1 to 8:2) to obtain the ferrocene derivative.
The chemical industry reduces the impact on the environment during synthesis,1271-55-2,Acetylferrocene,I believe this compound will play a more active role in future production and life.
Reference：
Article; Kiran Kumar, Chakka; Trivedi, Rajiv; Giribabu, Lingamallu; Niveditha, Surukonti; Bhanuprakash, Kotamarthi; Sridhar, Balasubramanian; Journal of Organometallic Chemistry; vol. 780; (2015); p. 20 – 29;,
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