While the job of a research scientist varies, most chemistry careers in research are based in laboratories,Synthetic Route of 1273-86-5, where research is conducted by teams following scientific methods and standards. In a patent,Which mentioned a new discovery about 1273-86-5
A series of enantioenriched ferrocenyl monophosphines imbued with both central and planar chirality were obtained catalytically (80?99% ee) via the kinetic resolution of 1,2-disubstituted planar chiral ferrocenyl enone racemates. The synthetic approach utilized a chiral palladacycle to facilitate the asymmetric hydrophosphination (AHP) as a means to achieve high stereoselectivity. The enantioenriched ferrocenylphosphine products could be protected and further recrystallized to obtain ees up to 99%. The modularity of the phosphine framework obtained was demonstrated via derivatization of its functional handles via a simple nucleophilic substitution to yield optically pure bisphosphines.
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Reference:
Iron Catalysis in Organic Synthesis | Chemical Reviews,
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion