Our Top Choice Compound: Ferrocenemethanol

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Conditions for the formation of intramolecular hydrogen bonds in alpha-metallocenylcarbinols of the iron subgroup (M = Fe, Ru, Os) are determined.The combination of IR spectral data with conformational calculations has revealed situations where hydrogen bonding with the metal atom is determined by conformational preference.General rules govering the influence of the nature of the metal atom and the effect of substituents in the carbinol group and the cyclopentadienyl rings on the formation constants and relative stability of OH…Me intramolecular hydrogen bonds, on the proton-donating ability of the OH group and on the competition between intra- and intermolecular hydrogen bonds during self-association in the crystal, are estabished.

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Reference:
Iron Catalysis in Organic Synthesis | Chemical Reviews,
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion