As a society publisher, everything we do is to support the scientific community – so you can trust us to always act in your best interests, Electric Literature of 16009-13-5, and get your work the international recognition that it deserves. Introducing a new discovery about 16009-13-5, Name is Hemin
The doxorubicin – hemin interaction was studied by absorption and emission spectroscopy. The absorption spectra outline two processes, in function of the concentration range of hemin. The fluorescence emission of doxorubicin shows a pronounced hypochromic effect in presence of hemin. The best fit was obtained using an (1:1) and (1:2) interaction for both methods. The doxorubicin – hematoporphyrin and doxorubicin – FeIII systems were also investigated in similar experimental conditions, in order to outline the possible binding sites involved in the interaction. The quenching effect of hematoporphyrin is smaller than that of hemin, the binding parameters indicated an (1:1) interaction and are smaller than the corresponding values for hemin. For the doxorubicin – FeIII system, the association constants for (1:1) and (1:2) complexes are in a reasonable agreement in both methods used. Our results are consistent with a two site binding model, where the Fe III ions of hemin are involved to a higher extent than the planar porphyrin moiety in the hemin – doxorubicin interaction.
Interested yet? This just the tip of the iceberg, You can reading other blog about 16009-13-5 .Electric Literature of 16009-13-5
Reference:
Iron Catalysis in Organic Synthesis | Chemical Reviews,
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion