Synthetic Route of 1271-48-3, In heterogeneous catalysis, catalysts provide a surface to which reactants bind in a process of adsorption. In homogeneous catalysis, catalysts are in the same phase as the reactants. In a document type is Article, and a compound is mentioned, 1271-48-3, name is 1,1′-Ferrocenedicarboxaldehyde, introducing its new discovery.
Synthesis of controlled pi-extended conjugate nanostructures of 1,1?-ferrocene
Synthesis of the (E,E)-1,1?-ferrocene nanostructures having controlled pi-extended conjugation was satisfactory carried out starting of 1?-[2-(1,3-dioxolan)]-1-formylferrocene (1). The molecular unit (E)-1?-[2-(1,3-dioxolan)]-1-[beta-(p-iodophenyl)ethenyl]ferrocene (2), was obtained in excellent yield by treatment of 1 with p-iodobenzyl triphenylphosphonium ylid followed by Z?E isomerization, catalyzed by iodine, in quantitative yield. Compound (E)-2 was transformed in (E)-1?-{2-(1,3-dioxolan)-1-[beta-[4-(3-hydroxy-3-methyl-but-1-ynyl)-phenyl]-ethenyl}ferrocene, (E)-4, by palladium catalyzed cross-coupling with 2-methyl-but-3-yn-2-ol. (E)-4 gives (E)-1-[beta-(4-ethynylphenyl)-ethenyl]-1?-[2-(1,3-dioxolan)]ferrocene (E)-5 by powder sodium hydroxide treatment. The molecular unit (E,E)-1-{beta-[4-(beta-(1?-formylferrocenyl)-ethenyl)-phenylethynyl]-phenyl]-ethenyl}-1?-formylferrocene, (E,E)-6, was synthesized by palladium catalyzed cross-coupling between the p-iodophenyl derivative (E)-2 and their ethynyl derivative (E)-5, in good yield. The (E,E)-1,1?-(p-iodophenyl)ethenyl ferrocene, (E,E)-7, was synthesized by reaction between 1,1?-diformylferrocene and the p-iodobenzyltriphenylphosphonium ylid, as a mixture of isomers which were purely isolated. Moreover, isomerization of the Z,Z and E,Z mixture to the E,E isomer, was induced by sunlight exposure, catalyzed by iodine, in quantitative yield. The (E,E)-1,1?-[beta-(4-ethynylphenyl)-ethenyl]ferrocene, (E,E)-10, was synthesized in good yield, by palladium catalyzed cross-coupling of compound (E,E)-7 with 2-methyl-but-3-yn-2-ol, followed by powder sodium hydroxide treatment.
Synthesis of controlled pi-extended conjugate nanostructures of 1,1?-ferrocene
The result showed that such a combination of chemo- and biocatalysis improved the catalytic yield more than two times compared with that of sole metal catalysis. We will look forword to the important role of 1271-48-3, and how the biochemistry of the body works.Synthetic Route of 1271-48-3
Reference£º
Iron Catalysis in Organic Synthesis | Chemical Reviews,
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion