Irreversible inhibitors are therefore the equivalent of poisons in heterogeneous catalysis. Safety of 1,1′-Diacetylferrocene, Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction by binding to a specific portion of an enzyme and thus slowing or preventing a reaction from occurring. In a patent,Which mentioned a new discovery about 1273-94-5
A […] of highly dilute preparation method, comprises the following steps: step 1), in the added into the dry CH […] in2 Cl2 , Pyridine and aniline derivatives stirring after; step 2), non-water treated CH2Cl2 dissolved 1, 1′ – ferrocene dicarboxylic acyl chloride, to slowly dropping in the […], after dropping the first reaction is carried out at room temperature, then slow heating, reflux; monitoring the reaction process for thin plate and, when one of the raw material point disappears, stopping the reaction; step 3), evaporate solution in dichloromethane, residual liquid water washing several times, the collected organic phase with anhydrous MgSO4 After drying the solvent evaporate under reduced pressure, then to admix the residual liquid in the silica gel, eluting agent selected: VPetroleum ether : VAcetic acid ethyl ester =3:1 elution, column purification, to obtain a final […]. The invention can simplify the link flourishing synthetic process, improve its productive rate with the fluorescence intensity, save the process cost. (by machine translation)
If you are interested in 1273-94-5, you can contact me at any time and look forward to more communication. The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules. Safety of 1,1′-Diacetylferrocene
Reference:
Iron Catalysis in Organic Synthesis | Chemical Reviews,
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion