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A has cytotoxicity to tumor targeting effects of ferrocene base Uygur formic acid/paclitaxel nano particle and its in the preparation of medicament for treating tumor application, belongs to the technical field of medicament. The invention preparation of nano particle retains the tretinoin inhibiting tumor stem cell proliferation, inducing activity, taxol can be carried at the same time the role of anti-personnel tumor stem cell outside of the common tumor cells; and the nano-particles to a tumor cell in a high concentration of reduced glutathione sensitive, into tumor cells can be rapidly cleavage after the release of the paclitaxel, exposed tretinoin functional group, their role; in the normal cell because less reductive glutathione content, will not be released or very few release, to reduce the toxic effect of the normal cells. At the same time, the nano-particle portable and transfer Micro – RNA into a cell to play a relevant role in, thus can be used for preparing medicaments for treating tumors. (by machine translation)
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Reference：
Iron Catalysis in Organic Synthesis | Chemical Reviews,
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion