You could be based in a university, combining chemical research with teaching; in a pharmaceutical company, working on developing and trialing new drugs; Application of 16009-13-5, or in a public-sector research center, helping to ensure national healthcare provision keeps pace with new discoveries.In a article, mentioned the application of 16009-13-5, Name is Hemin, molecular formula is C34H32ClFeN4O4
Complexation of iron(II) protoporphyrin IX (Fe2+PP) into a genetically engineered heme pocket on recombinant human serum albumin (rHSA) creates an artificial hemoprotein which can bind O2 reversibly at room temperature. Here we highlight a crucial role of a basic amino acid triad the entrance of the heme pocket in rHSA (Arg-114, His-146, Lys-190) for O 2 and CO binding to the prosthetic Fe2+PP group. Replacing His-146 and/or Lys-190 with Arg resolved the structured heterogeneity of the possible two complexing modes of the porphyrin and afforded a single O 2 and CO binding affinity. Resonance Raman spectra show only one geometry of the axial His coordination to the central ferrous ion of the Fe 2+PP.
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Reference:
Iron Catalysis in Organic Synthesis | Chemical Reviews,
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion