Ferrocenecarboxaldehyde, cas is 12093-10-6, it is a common heterocyclic compound, the iron-catalyst compound, its synthesis route is as follows.,12093-10-6
General procedure: To a clean and dry round bottom flask with a septum, 3-5mmol of the ferrocenylketone were added and approximately 20mL of dimethoxyethane (DME) were transferred with a positive nitrogen pressure; the mixture was stirred to obtain a reddish solution. 0.75equivalents of lithium aluminum hydride (1M in tetrahydrofuran) were added, and a change of color from red to yellow in the solution was observed. The reaction was stopped after 30min at room temperature; complete transformation was confirmed with TLC. After this time, Glauber’s salt was added and the mixture was stirred until a formation of a granular precipitate was observed. The mixture was filtered, and the solvent was eliminated to obtain yellow to orange oils or solids. The compounds were employed directly for following reactions without further purification.
12093-10-6 is used more and more widely, we look forward to future research findings about Ferrocenecarboxaldehyde
Reference£º
Article; Garcia-Barrantes, Pedro M.; Lamoureux, Guy V.; Perez, Alice L.; Garcia-Sanchez, Rory N.; Martinez, Antonio R.; San Feliciano, Arturo; European Journal of Medicinal Chemistry; vol. 70; (2013); p. 548 – 557;,
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