Name is Ferrocenecarboxaldehyde, as a common heterocyclic compound, it belongs to iron-catalyst compound, and cas is 12093-10-6, its synthesis route is as follows.,12093-10-6
General procedure: A solution of pure TsNHNH2 (15 mmol) in methanol (30 mL) was stirred and heated to 60 C until the TsNHNH2 dissolved. The mixture was cooled to room temperature. Then a solution of ferrocenylketone (10 mmol) in methanol was dropped into the mixture slowly. After approximately 0.5-2 h, the crude products could be obtained as solid precipitate. The precipitate was washed with petroleum ether then removed in vacuo to give the pure products. In general, the yields were 68-86 %. Because of the relatively low activity of some ketones, their reactions at room temperature may be incomplete. They should be reacted in refluxing methanol. The reaction could be monitored by TLC.
With the complex challenges of chemical substances, we look forward to future research findings about Ferrocenecarboxaldehyde
Reference£º
Article; Ling, Li; Hu, Jianfeng; Huo, Yanhong; Zhang, Hao; Tetrahedron; vol. 73; 1; (2017); p. 86 – 97;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
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