Analyzing the synthesis route of 1271-55-2

With the synthetic route has been constantly updated, we look forward to future research findings about Acetylferrocene,belong iron-catalyst compound

As a common heterocyclic compound, it belong iron-catalyst compound,Acetylferrocene,1271-55-2,Molecular formula: C12H12FeO,mainly used in chemical industry, its synthesis route is as follows.,1271-55-2

General procedure: A mixture of 1.14 g (5 mmol) of acetylferrocene, 5 mmol of the corresponding aromatic aldehyde, 50 mL of ethanol, and 2.5 g (45 mmol) of potassium hydroxide was stirred for 12 h at room temperature. The mixture was poured onto ice, and the precipitate was filtered off and purified by silica gel column chromatography using methylene chloride (2, 4) or methylene chloride-hexane (19 : 1) (3) as eluent. 1-Ferrocenyl-3-(4-fluorophenyl)prop-2-en-1-one(2). Yield 85%,

With the synthetic route has been constantly updated, we look forward to future research findings about Acetylferrocene,belong iron-catalyst compound

Reference£º
Article; Antuf?eva; Zhulanov; Dmitriev; Mokrushin; Shklyaeva; Abashev; Russian Journal of General Chemistry; vol. 87; 3; (2017); p. 470 – 478; Zh. Obshch. Khim.; vol. 87; 3; (2017); p. 465 – 473,9;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion