1273-94-5, Name is 1,1′-Diacetylferrocene, belongs to iron-catalyst compound, is a common compound. 1273-94-5In an article, authors is Barik, Tulasi, once mentioned the new application about 1273-94-5.
Bioactive 1,1?-unsymmetrical bi-functional ferrocenyl compounds using a novel solvent free one pot multicomponent reaction method
A solvent free synthetic method using rice husk ash (RHA) as solid support has been designed for selective functionalization and preparation of novel 1,1?- unsymmetrically bi-functionalized ferrocenyl compounds. The selectively functionalized intermediate compound, Ferrocenyl-1-acetyl-1?-thiosemicarbazone, has been structurally characterized using single crystal X-ray diffraction technique which revealed distinct inter-molecular hydrogen bonding interactions across the thiosemicarbazone chains. Cytotoxic evaluation of five different unsymmetrically bi-functionalized thiosemicarbazone – hydrazone compounds showed potent activity against human leukemia (THP-1) cell line. The unsymmetrical ferrocenyl compounds also showed strong BSA and DNA binding interactions and reversible redox properties.
Bioactive 1,1?-unsymmetrical bi-functional ferrocenyl compounds using a novel solvent free one pot multicomponent reaction method
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Reference£º
Iron Catalysis in Organic Synthesis | Chemical Reviews,
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion