Category: 12126-50-0

Analyzing the synthesis route of 12126-50-0

The chemical industry reduces the impact on the environment during synthesis,12126-50-0,Bis(pentamethylcyclopentadienyl)iron(II),I believe this compound will play a more active role in future production and life.

12126-50-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Bis(pentamethylcyclopentadienyl)iron(II), cas is 12126-50-0,the iron-catalyst compound, it is a common compound, a new synthetic route is introduced below.

Salt 1 was synthesized as follows. Under a nitrogen atmosphere,SO2Cl2 (0.025 mL, 0.31 mmol) was added dropwise to a dichloromethanesolution (0.5 mL) of [FeCp*2] (48 mg, 0.15 mmol) andstirred for 15 min. The solvent was then evaporated under reducedpressure and vacuum dried. The resulting dark green solid of[FeCp*2]Cl was dissolved in water (0.5 mL), to which an aqueoussolution (0.2 mL) of K [CH2BrBF3] (54 mg, 0.27 mmol) was added and stirred for 15 min. The resulting precipitate was collected by filtration and washed with ether, followed by drying under vacuumto obtain the desired product as a dark green solid. Recrystallizationby slow cooling (-40 C) of an ether-dichloromethane solution ofthe solid afforded dark green block crystals of 1 (31.5 mg, yield 43%). Anal. Calcd. For C21H32F3BBrFe: C, 51.68; H, 6.65; N, 0.00.Found: C, 51.88; H, 7.05; N, 0.00. IR (cm-1): 2949, 1474, 1424, 1381,1186, 1124, 1104, 1081, 1043, 1025, 996, 968, 954, 742, 722, 619, 593,531.

The chemical industry reduces the impact on the environment during synthesis,12126-50-0,Bis(pentamethylcyclopentadienyl)iron(II),I believe this compound will play a more active role in future production and life.

Reference：
Article; Kimata, Hironori; Mochida, Tomoyuki; Journal of Organometallic Chemistry; vol. 895; (2019); p. 23 – 27;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

 

Some tips on Bis(pentamethylcyclopentadienyl)iron(II)

With the complex challenges of chemical substances, we look forward to future research findings about 12126-50-0,belong iron-catalyst compound

As a common heterocyclic compound, it belongs to iron-catalyst compound, name is Bis(pentamethylcyclopentadienyl)iron(II), and cas is 12126-50-0, its synthesis route is as follows.,12126-50-0

A yellow-orange solution of decamethylferrocene(16 mg, 0.05 mmol) in CH2Cl2(0.1 mL) was placed in a test tube (5 mm inner diameter),and a colorless solution of Ph(Cl)C=C(Ph)TeCl3 (22 mg, 0.05 mmol) in CH2Cl2 (0.2 mL)was carefully added dropwise. The contact areabetween the solutions acquired a green color typical ofthe ferrocenium cation, but no precipitation or formationof solid particles was observed in the contact area.The test tube was purged with argon, sealed with severalparafilm layers, and left in the dark at room temperature.After 5 days, the solvent evaporated almostcompletely and uniform green prismatic crystals, suitablefor X-ray diffraction, were deposited on the tubewall.

With the complex challenges of chemical substances, we look forward to future research findings about 12126-50-0,belong iron-catalyst compound

Reference£º
Article; Torubaev, Yu. V.; Lyssenko; Popova; Russian Journal of Coordination Chemistry; vol. 45; 11; (2019); p. 788 – 794; Koord. Khim.; vol. 45; 11; (2019); p. 684 – 690,7;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

 

The important role of 12126-50-0

With the complex challenges of chemical substances, we look forward to future research findings about Bis(pentamethylcyclopentadienyl)iron(II)

Name is Bis(pentamethylcyclopentadienyl)iron(II), as a common heterocyclic compound, it belongs to iron-catalyst compound, and cas is 12126-50-0, its synthesis route is as follows.,12126-50-0

Decamethylferrocene (A) (4.80 g, 14.7 mmol) was placed in a round bottomed flask equipped with a magnetic stirrer bar. Fresh finely ground barium manganate (18.77 g, 73.6 mmol, 5 eq) was then added to the flask. The solids were then suspended in a mixture of dry benzene (20 cm3) and drydiethyl ether (20 cm3). The flask was then sealed and placed under a nitrogen atmosphere. The dark blue slurry was then sonicated for 45 mins. After this time the flask was removed from the sonicater and heated at 45 C for 16 hours. After this time the dark slurry was filtered through a pad of celite and the solids washed with EtOAc (250 cm3) until the washings ran clear. The red solution was then concentrated in vacuo to give a red solid. Purification by silica chromatography eluting with 5%EtOAc : nHex + 2% TEA gave the product nonamethylferrocene carboxaldehyde (B) as a dark red crystalline solid (1.19 g, 23%).?H NIVIR (300 IVIHz, CDC13) OH: 9.91 (s, 1H), 1.92 (s, 6H), 1.71 (s, 6H), 1.59 (s, 15H). ?3C NIVIR (75 IVIHz, CDC13) Oc: 195.6, 86.0, 82.7, 80.6, 78.3, 72.5, 9.3, 9.3, 8.9. HRMS (ESI iTOF) calculated for C20H29FeO m/z 341.1484 found 341.1485 (m/z + H).

With the complex challenges of chemical substances, we look forward to future research findings about Bis(pentamethylcyclopentadienyl)iron(II)

Reference£º
Patent; ATLAS GENETICS LIMITED; MARSH, Barrie J.; FROST, Christopher G.; SHARP, Jonathan; WO2015/52516; (2015); A1;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

 

New learning discoveries about 12126-50-0

With the synthetic route has been constantly updated, we look forward to future research findings about Bis(pentamethylcyclopentadienyl)iron(II),belong iron-catalyst compound

Bis(pentamethylcyclopentadienyl)iron(II), cas is 12126-50-0, it is a common heterocyclic compound, the iron-catalyst compound, its synthesis route is as follows.,12126-50-0

A premixture was prepared by dissolving (i) 0.76 g (4.09 mMoles) of decamethyl ferrocene and (ii) 0.48 g (4.09 mMoles) of isoamyl nitrite in 15 mL CHCI3. A reaction mixture was prepared by adding to said premixture a solution of (iii) 1.15 g (4.09 mMoles) Bis(trifluormethylsulfonyl)imide in 15 mL CHCI3 at room temperature under stirring. The color of the reaction mixture quickly turned from yellow-orange to dark green upon addition of the solution of (iii), and gas evolved. The reaction mixture was heated under reflux conditions up to its boiling point, and was kept at its boiling point under reflux conditions for one hour. Then the reaction mixture was allowed to cool and the liquid phase was removed by evaporation so that a solid residue was obtained. The obtained solid residue was digested using either diethyl ether or toluene as the digesting agent. The digesting agent was removed from the digested solid residue by filtration. The digested solid residue was collected and dried at 25 C for 6 hours in vacuo. The obtained product is a dark green powder. The amount of the obtained product was 1 .7 g, corresponding to a yield of 89.2 % based on the initial amount of decamethyl ferrocene. The chemical composition of the obtained product was analyzed by elemental analysis. The results are listed in the table below. For comparison, the theoretical weight percentage of each element in decamethyl ferrocenium bis(trifluoromethylsulfonyl)imide are given. The deviations between the calculated and the measured weight percentages are within the accuracy of measurement. element Calculated content/ Measured content

With the synthetic route has been constantly updated, we look forward to future research findings about Bis(pentamethylcyclopentadienyl)iron(II),belong iron-catalyst compound

Reference£º
Patent; BASF SE; HEMGESBERG, Maximilian; FRANK, Juergen; NOeRENBERG, Ralf; (28 pag.)WO2017/97969; (2017); A1;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

 

Analyzing the synthesis route of 12126-50-0

With the synthetic route has been constantly updated, we look forward to future research findings about Bis(pentamethylcyclopentadienyl)iron(II),belong iron-catalyst compound

As a common heterocyclic compound, it belong iron-catalyst compound,Bis(pentamethylcyclopentadienyl)iron(II),12126-50-0,Molecular formula: C20H30Fe,mainly used in chemical industry, its synthesis route is as follows.,12126-50-0

Salt 1 was synthesized as follows. Under a nitrogen atmosphere,SO2Cl2 (0.025 mL, 0.31 mmol) was added dropwise to a dichloromethanesolution (0.5 mL) of [FeCp*2] (48 mg, 0.15 mmol) andstirred for 15 min. The solvent was then evaporated under reducedpressure and vacuum dried. The resulting dark green solid of[FeCp*2]Cl was dissolved in water (0.5 mL), to which an aqueoussolution (0.2 mL) of K [CH2BrBF3] (54 mg, 0.27 mmol) was added and stirred for 15 min. The resulting precipitate was collected by filtration and washed with ether, followed by drying under vacuumto obtain the desired product as a dark green solid. Recrystallizationby slow cooling (-40 C) of an ether-dichloromethane solution ofthe solid afforded dark green block crystals of 1 (31.5 mg, yield 43%). Anal. Calcd. For C21H32F3BBrFe: C, 51.68; H, 6.65; N, 0.00.Found: C, 51.88; H, 7.05; N, 0.00. IR (cm-1): 2949, 1474, 1424, 1381,1186, 1124, 1104, 1081, 1043, 1025, 996, 968, 954, 742, 722, 619, 593,531.

With the synthetic route has been constantly updated, we look forward to future research findings about Bis(pentamethylcyclopentadienyl)iron(II),belong iron-catalyst compound

Reference£º
Article; Kimata, Hironori; Mochida, Tomoyuki; Journal of Organometallic Chemistry; vol. 895; (2019); p. 23 – 27;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

 

Simple exploration of 12126-50-0

12126-50-0 Bis(pentamethylcyclopentadienyl)iron(II) 22218084, airon-catalyst compound, is more and more widely used in various.

12126-50-0, Bis(pentamethylcyclopentadienyl)iron(II) is a iron-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,12126-50-0

A yellow-orange solution of decamethylferrocene(16 mg, 0.05 mmol) in CH2Cl2(0.1 mL) was placed in a test tube (5 mm inner diameter),and a colorless solution of Ph(Cl)C=C(Ph)TeCl3 (22 mg, 0.05 mmol) in CH2Cl2 (0.2 mL)was carefully added dropwise. The contact areabetween the solutions acquired a green color typical ofthe ferrocenium cation, but no precipitation or formationof solid particles was observed in the contact area.The test tube was purged with argon, sealed with severalparafilm layers, and left in the dark at room temperature.After 5 days, the solvent evaporated almostcompletely and uniform green prismatic crystals, suitablefor X-ray diffraction, were deposited on the tubewall.

12126-50-0 Bis(pentamethylcyclopentadienyl)iron(II) 22218084, airon-catalyst compound, is more and more widely used in various.

Reference£º
Article; Torubaev, Yu. V.; Lyssenko; Popova; Russian Journal of Coordination Chemistry; vol. 45; 11; (2019); p. 788 – 794; Koord. Khim.; vol. 45; 11; (2019); p. 684 – 690,7;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

 

Some tips on 12126-50-0

12126-50-0 Bis(pentamethylcyclopentadienyl)iron(II) 22218084, airon-catalyst compound, is more and more widely used in various.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12126-50-0,Bis(pentamethylcyclopentadienyl)iron(II),as a common compound, the synthetic route is as follows.

Decamethylferrocene (A) (4.80 g, 14.7 mmol) was placed in a round bottomed flask equipped with a magnetic stirrer bar. Fresh finely ground barium manganate (18.77 g, 73.6 mmol, 5 eq) was then added to the flask. The solids were then suspended in a mixture of dry benzene (20 cm3) and drydiethyl ether (20 cm3). The flask was then sealed and placed under a nitrogen atmosphere. The dark blue slurry was then sonicated for 45 mins. After this time the flask was removed from the sonicater and heated at 45 C for 16 hours. After this time the dark slurry was filtered through a pad of celite and the solids washed with EtOAc (250 cm3) until the washings ran clear. The red solution was then concentrated in vacuo to give a red solid. Purification by silica chromatography eluting with 5%EtOAc : nHex + 2% TEA gave the product nonamethylferrocene carboxaldehyde (B) as a dark red crystalline solid (1.19 g, 23%).?H NIVIR (300 IVIHz, CDC13) OH: 9.91 (s, 1H), 1.92 (s, 6H), 1.71 (s, 6H), 1.59 (s, 15H). ?3C NIVIR (75 IVIHz, CDC13) Oc: 195.6, 86.0, 82.7, 80.6, 78.3, 72.5, 9.3, 9.3, 8.9. HRMS (ESI iTOF) calculated for C20H29FeO m/z 341.1484 found 341.1485 (m/z + H).

12126-50-0 Bis(pentamethylcyclopentadienyl)iron(II) 22218084, airon-catalyst compound, is more and more widely used in various.

Reference£º
Patent; ATLAS GENETICS LIMITED; MARSH, Barrie J.; FROST, Christopher G.; SHARP, Jonathan; WO2015/52516; (2015); A1;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

 

Downstream synthetic route of 12126-50-0

As the paragraph descriping shows that 12126-50-0 is playing an increasingly important role.

12126-50-0, Bis(pentamethylcyclopentadienyl)iron(II) is a iron-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A premixture was prepared by dissolving (i) 0.76 g (4.09 mMoles) of decamethyl ferrocene and (ii) 0.48 g (4.09 mMoles) of isoamyl nitrite in 15 mL CHCI3. A reaction mixture was prepared by adding to said premixture a solution of (iii) 1.15 g (4.09 mMoles) Bis(trifluormethylsulfonyl)imide in 15 mL CHCI3 at room temperature under stirring. The color of the reaction mixture quickly turned from yellow-orange to dark green upon addition of the solution of (iii), and gas evolved. The reaction mixture was heated under reflux conditions up to its boiling point, and was kept at its boiling point under reflux conditions for one hour. Then the reaction mixture was allowed to cool and the liquid phase was removed by evaporation so that a solid residue was obtained. The obtained solid residue was digested using either diethyl ether or toluene as the digesting agent. The digesting agent was removed from the digested solid residue by filtration. The digested solid residue was collected and dried at 25 C for 6 hours in vacuo. The obtained product is a dark green powder. The amount of the obtained product was 1 .7 g, corresponding to a yield of 89.2 % based on the initial amount of decamethyl ferrocene. The chemical composition of the obtained product was analyzed by elemental analysis. The results are listed in the table below. For comparison, the theoretical weight percentage of each element in decamethyl ferrocenium bis(trifluoromethylsulfonyl)imide are given. The deviations between the calculated and the measured weight percentages are within the accuracy of measurement. element Calculated content/ Measured content

As the paragraph descriping shows that 12126-50-0 is playing an increasingly important role.

Reference£º
Patent; BASF SE; HEMGESBERG, Maximilian; FRANK, Juergen; NOeRENBERG, Ralf; (28 pag.)WO2017/97969; (2017); A1;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

 

Analyzing the synthesis route of 12126-50-0

The synthetic route of 12126-50-0 has been constantly updated, and we look forward to future research findings.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12126-50-0,Bis(pentamethylcyclopentadienyl)iron(II),as a common compound, the synthetic route is as follows.

Salt 1 was synthesized as follows. Under a nitrogen atmosphere,SO2Cl2 (0.025 mL, 0.31 mmol) was added dropwise to a dichloromethanesolution (0.5 mL) of [FeCp*2] (48 mg, 0.15 mmol) andstirred for 15 min. The solvent was then evaporated under reducedpressure and vacuum dried. The resulting dark green solid of[FeCp*2]Cl was dissolved in water (0.5 mL), to which an aqueoussolution (0.2 mL) of K [CH2BrBF3] (54 mg, 0.27 mmol) was added and stirred for 15 min. The resulting precipitate was collected by filtration and washed with ether, followed by drying under vacuumto obtain the desired product as a dark green solid. Recrystallizationby slow cooling (-40 C) of an ether-dichloromethane solution ofthe solid afforded dark green block crystals of 1 (31.5 mg, yield 43%). Anal. Calcd. For C21H32F3BBrFe: C, 51.68; H, 6.65; N, 0.00.Found: C, 51.88; H, 7.05; N, 0.00. IR (cm-1): 2949, 1474, 1424, 1381,1186, 1124, 1104, 1081, 1043, 1025, 996, 968, 954, 742, 722, 619, 593,531.

The synthetic route of 12126-50-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Kimata, Hironori; Mochida, Tomoyuki; Journal of Organometallic Chemistry; vol. 895; (2019); p. 23 – 27;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion