Iron catalyst

As a common heterocyclic compound, it belongs to iron-catalyst compound, name is Ferrocenemethanol, and cas is 1273-86-5, its synthesis route is as follows.

General procedure: To a mixture of 1.0mmol of ferrocene alcohol and 1.0mmol of the corresponding nitroimidazole in 1.0ml of methylene dichloride, 0.18ml of 45% aqueous solution of fluoroboric acid was added under vigorous stirring. The agitation was continued for 5min then diethyl ether (15ml), the same amount of cold water, and 5-10mg of ascorbic acid were added to the reaction flask. After vigorous shaking of the mixture, the organic solution was separated, washed with cold water (3¡Á15ml), the solvents were removed in vacuo, and the residue was dried over CaCl2 in a desiccator.

1273-86-5, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,1273-86-5 ,Ferrocenemethanol, other downstream synthetic routes, hurry up and to see

Reference£º
Article; Snegur, Lubov V.; Lyapunova, Maria V.; Verina, Daria D.; Kachala, Vadim V.; Korlyukov, Alexander A.; Ilyin, Mikhail M.; Davankov, Vadim A.; Ostrovskaya, Larissa A.; Bluchterova, Natalia V.; Fomina, Margarita M.; Malkov, Victor S.; Nevskaya, Kseniya V.; Pershina, Alexandra G.; Simenel, Alexander A.; Journal of Organometallic Chemistry; vol. 871; (2018); p. 10 – 20;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

1287-16-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Ferrocenylacetic acid, cas is 1287-16-7,the iron-catalyst compound, it is a common compound, a new synthetic route is introduced below.

1) 1.2 mmol of ferrocenyl acetic acid and 1 mmol of 3- (2,4-dichlorophenyl) -4-amino-5-mercapto-1,2,4-triazole were weighed out,Added to a dry 250mL single-necked flask,Then p-toluenesulfonic acid 0.12 mmol,7 mL of DMF was further added thereto,The glass rod is stirred to dissolve it.2)The round bottom flask was placed in a microwave reactor,370W under irradiation once every 30s,Irradiation duration of 4min.After irradiation,cool down.3)Pour it into a crushed beaker,With potassium carbonate and potassium hydroxide pH = 7,Placed overnight,filter,Washed,dry,Thus, 3- (2,4-dichlorophenyl) -6-ferrocenylmethylene-1,2,4-triazolo [3.4-b] -1,3,4-thiadiazole was obtained product,Using a solvent of DMF and absolute ethanol in a volume ratio of 4: 1 mixed solvent,The crude product was recrystallized,That is, a brown solid,The yield is 82%

The chemical industry reduces the impact on the environment during synthesis,1287-16-7,Ferrocenylacetic acid,I believe this compound will play a more active role in future production and life.

Reference£º
Patent; Shaanxi University of Science and Technology; Liu, Yuting; Song, Simeng; Yin, Dawei; Jiang, Shanshan; Liu, Beibei; Yang, Aning; Wang, Jinyu; Lyu, Bo; (13 pag.)CN104231004; (2017); B;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

As a common heterocyclic compound, it belongs to iron-catalyst compound, name is Ferrocenecarboxylic acid, and cas is 1271-42-7, its synthesis route is as follows.

Ferrocene (6.0 g, 32 mmol) and potassium tert-butoxide (0.46 g, 4.08 mmol) were completely dissolved in dry THF (300 mL). The orange solution was cooled to -78 0C when tertbutyllithium (34.0 mL, 64.5 mmol, 1 .9 M in pentane) was added dropwise over a period of 15 mm, with the temperature maintained below -70 00. The reaction mixture was stirred at -78Cfor 1 h and then poured on a slurry of dry ice (excess) and diethyl ether. The mixture was warmed to room temperature overnight and extracted with an aqueous solution of sodium hydroxide (0.75 N, 4 x 250 mL). The combined aqueous layers were neutralized with hydrochloric acid (pH > 4) and the resulting orange solid was extracted with Et20 (4 x 250 mL) until the organic layer remained colourless. The combined organic layers were filtered toremove traces of ferrocenedicarboxylic acid, dried over MgSO4, filtered and the solvent wasevaporated under reduced pressure to give ferrocenecarboxylic acidas an orange solid in35% yield. After suspending the ferrocenecarboxylic acid (462 mg, 2.01 mmol) in dry CH2CI2(23 mL), oxalyl chloride (1100 iL, 13.64 mmol) in dry CH2CI2 (10 mL) was added dropwise tothe reaction mixture whereby the orange suspension turned dark red. The reaction mixturewas refluxed for 2 h and then stirred overnight at room temperature. The solvent was thenremoved under vacuum. The product was not purified and used immediately for the next synthetic step.

1271-42-7, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,1271-42-7 ,Ferrocenecarboxylic acid, other downstream synthetic routes, hurry up and to see

Reference£º
Patent; UNIVERSITAeT ZUeRICH; THE UNIVERSITY OF MELBOURNE; HESS, Jeannine; PATRA, Malay; GASSER, Gilles; JABBAR, Abdul; GASSER, Robin B.; WO2015/928; (2015); A1;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

Name is Ferrocenemethanol, as a common heterocyclic compound, it belongs to iron-catalyst compound, and cas is 1273-86-5, its synthesis route is as follows.

General procedure: Under a nitrogen atmosphere, ferrocenyl methanol (216 mg, 1 mmol) and 1-methylimidazole (240 mg, 3 mmol) were dissolved in 3 mL of acetic acid and stirred for 5 h at 60 C. Volatiles were evaporated, and a solution of NH4PF6 (1.11 g, 6.2 mmol) in EtOH (5 mL) was added. After the solution had been stirred for 2 h at room temperature, the solvent was evaporated. CH2Cl2 was added to the solution, and the solution was filtered through Celite. The solvent was removed, and the residues were recrystallization from acetone/ether afforded 0.30 g (71% yield) of 1b as yellow needles. 1H NMR (600 MHz, CD3COCD3): delta (ppm) 4.08 (s, 3H, CH3), 4.26 (s, 5H, C5H5), 4.33 (s, 2H, C5H4), 4.54 (s, 2H, C5H4), 5.44 (s, 2H, CH2), 7.71 (s, 1H, CH=CH), 7.76 (s, 1H, CH=CH), 9.01 (s, 1H, NCH=N). 13C NMR (400MHz, CD3COCD3): delta (ppm) 36.92 (CH3), 50.13 (CH2), 69.56, 69.96, 70.10, 80.54 (Cp-C), 122.87, 124.54, 136.59 (imidazole-C).

1273-86-5, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,1273-86-5 ,Ferrocenemethanol, other downstream synthetic routes, hurry up and to see

Reference£º
Article; Kong, Dandan; Weng, Tanqing; He, Wenxue; Liu, Bin; Jin, Shan; Hao, Xiao; Liu, Shenghua; Journal of Organometallic Chemistry; vol. 727; (2013); p. 19 – 27;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

As a common heterocyclic compound, it belongs to iron-catalyst compound, name is (1-Hydroxyethyl)ferrocene, and cas is 1277-49-2, its synthesis route is as follows.

Under an inert atmosphere, to a solution of alcohol 3 (2.00 g, 8.69mmol) and DMAP (53.1 mg, 0.43 mmol) in anhydrous CH 2 Cl 2 (20 mL)was added dropwise Et 3 N (3.64 mL, 26.1 mmol) at 0 C, followed byaddition of methanesulfonyl chloride (0.45 mL, 9.14 mmol). The reac-tion mixture was then stirred at r.t. for 4 h. The reaction wasquenched by addition of 5% solution of NaHCO 3 (40 mL), and the mix-ture was extracted with CHCl 3 (3 ¡Á 100 mL). Collected organic layerswere washed with brine (100 mL), dried over Na 2 SO 4 , filtrated, andsolvent was removed under reduced pressure to afford the crudeproduct. The crude product was purified by chromatography on Al 2 O 3(hexanes/EtOAc, 9:1; R f = 0.8) to afford target product 4.Yield: 1.59 g (86%); yellow-orange solid; mp 50-52 C (lit. 15 51-52 C).IR (ATR): 1623, 1408, 1103, 1045, 998, 894, 810, 726, 517, 477, 446cm -1 .1 H NMR (600 MHz, CDCl 3 ): delta = 6.46 (dd, J = 17.4, 10.7 Hz, 1 H), 5.34 (d,J = 17.5 Hz, 1 H), 5.03 (d, J = 10.7 Hz, 1 H), 4.36 (s, 2 H), 4.21 (s, 2 H),4.11 (s, 5 H).13 C NMR (151 MHz, CDCl 3 ): delta = 134.7, 111.1, 83.7, 69.3, 68.7, 66.8.HRMS (ESI): m/z calcd for [M + H + ] C 12 H 13 Fe + : 213.0367; found:213.0359.Obtained spectral data are in agreement with those of the commer-cially available product.

1277-49-2, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,1277-49-2 ,(1-Hydroxyethyl)ferrocene, other downstream synthetic routes, hurry up and to see

Reference£º
Article; Plevova, Kristina; Mudrakova, Brigita; ?ebesta, Radovan; Synthesis; vol. 50; 4; (2018); p. 760 – 763;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

14024-18-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Iron(III) acetylacetonate, cas is 14024-18-1,the iron-catalyst compound, it is a common compound, a new synthetic route is introduced below.

In a 100 mL Schlenk tube 1.00 g (2.83 mmol) of Iron(III)-acetylacetonate (Fe(AcAc)3), synthesized as reported in Bondioliet al., [13] was dissolved in different amounts of BzOH in order to evaluate the effect of the Fe(AcAc)3:BzOH ratio on the powder properties (see composition details in Table 1). The reaction was left stirring at room temperature for 15 min and then heated to 200C in an oil bath for 48 h. The main reaction occurring in the solvothermal treatment of Iron(III)-acetylacetonate in benzyl alcoholis summarized in the scheme of Fig. 1. After reaction a stable suspension was obtained. To better characterize the inorganic phase, the obtained powders were dispersed in methanol with an ultrasonic bath and centrifuged at 4000 rpm for 60 min; the powders were washed, centrifuged till the obtainment of a colourless liquid phase and finally dried under reduced pressure.

The chemical industry reduces the impact on the environment during synthesis,14024-18-1,Iron(III) acetylacetonate,I believe this compound will play a more active role in future production and life.

Reference£º
Article; Sciancalepore, Corrado; Bondioli, Federica; Messori, Massimo; Barrera, Gabriele; Tiberto, Paola; Allia, Paolo; Polymer; vol. 59; (2015); p. 278 – 289;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

1273-86-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Ferrocenemethanol, cas is 1273-86-5,the iron-catalyst compound, it is a common compound, a new synthetic route is introduced below.

To a 10 ml Schlek reaction tube under a high-purity nitrogen atmosphere was added 0.20 mmol of benzoquinoline triphenylphosphine iridium hydrogen (16), lmmol of phenylacetylene, 2.3 mmol of ferrocene methanol, 0.8 mmol of sodium hydroxide and 3 ml of dioxane were charged. The reaction tube was replaced with nitrogen three times and then heated to 110 C with an oil bath under magnetic stirring. The reaction was refluxed for 36 hours. The filtrate was concentrated using a rotary evaporator and the remaining residue was purified by chromatography on oil (100 mL). The residue was purified by flash chromatography on silica gel eluting with an oil bath and the bath was cooled to room temperature. Ether as eluent, and separated by silica gel thin layer chromatography to obtain pure product 1-ferrocenyl-3-phenyl-1-propanone in a yield of 96%.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Ferrocenemethanol, 1273-86-5

Reference£º
Patent; Luoyang Normal University; Li, Xiao Dong; Li, gongmei; Xu, Chen; Hao, Xin Qi; Xiao, Zhi Qiang; (10 pag.)CN103242372; (2016); B;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

1273-82-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Aminoferrocene, cas is 1273-82-1,the iron-catalyst compound, it is a common compound, a new synthetic route is introduced below.

General procedure: Organometallic sulfonamides were prepared following a modification of the procedure described by Alberto and co-workers [41]. An equimolar amount of pyridine was added at room temperature to a solution containing 50mg of P2 or P3 in 7.0mL of anhydrous CH2Cl2. After 15min, the corresponding sulfonyl chloride derivative was added, and the reaction mixture was heated under reflux for 24h. The resulting solution was dried under vacuum. The crude product was purified using silica gel liquid chromatography and a mixture of CH2Cl2/hexane (4:1) as the eluent. All compounds were recrystallized from an acetone/hexane (1:5) mixture by slow evaporation.

The chemical industry reduces the impact on the environment during synthesis,1273-82-1,Aminoferrocene,I believe this compound will play a more active role in future production and life.

Reference£º
Article; Quintana, Cristobal; Silva, Gisella; Klahn, A. Hugo; Artigas, Vania; Fuentealba, Mauricio; Biot, Christophe; Halloum, Iman; Kremer, Laurent; Novoa, Nestor; Arancibia, Rodrigo; Polyhedron; vol. 134; (2017); p. 166 – 172;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

Name is Ferrocenemethanol, as a common heterocyclic compound, it belongs to iron-catalyst compound, and cas is 1273-86-5, its synthesis route is as follows.

General procedure: 1.1 mmol of triethylamine was added to a stirred mixture of 1.0 mmol of metallocene alcohol (7, 8, 12) or 0.45 mmol of ferrocene diol (10, 11) and 1.0 mmol of 4,5-dichloroisothiazole- or 5-arylisoxazole-3-carbonyl chloride in 50 mL of diethyl ether at 20-23C. The reaction mixture was stirred at that temperature during 24 h. The precipitated triethylamine hydrochloride was filtered off and washed with diethyl ether (5 ¡Á 10 mL). The filtrate was washed with 10 % aqueous NaCl and 5 % aqueous NaHCO3. The solvent was removed, and the residue was recrystallized from a benzene-hexane (2 : 1) mixture (14, 15, 19, and 20) or from hexane (16,17, 21, and 22). 3,4,4-Trichloro-1-cymantrenylbut-3-en-1-yl 4,5-dichloroisothiazole-3-carboxylate 18 was obtained as a viscous oil and was used without further purification.

1273-86-5, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,1273-86-5 ,Ferrocenemethanol, other downstream synthetic routes, hurry up and to see

Reference£º
Article; Potkin; Dikusar; Kletskov; Petkevich; Semenova; Kolesnik; Zvereva; Zhukovskaya; Rosentsveig; Levkovskaya; Zolotar; Russian Journal of General Chemistry; vol. 86; 2; (2016); p. 338 – 343; Zh. Obshch. Khim.; vol. 86; 2; (2016); p. 338 – 343,6;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion

As a common heterocyclic compound, it belongs to iron-catalyst compound, name is Ferrocenecarboxaldehyde, and cas is 12093-10-6, its synthesis route is as follows.

General procedure: To a stirred suspension of p-toluenesulfonyl hydrazide (1eq.) in water (12mL) and three drops of HCl 32%, the formyl or acetyl organometallic precursor (1eq.) was added. The resulting mixture was stirred for 18h at room temperature. The precipitate obtained was washed with water (2¡Á10mL) and dried under vacuum. The hydrazone derivatives were recrystallized from acetone/hexane (1:5) at -18C

12093-10-6, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,12093-10-6 ,Ferrocenecarboxaldehyde, other downstream synthetic routes, hurry up and to see

Reference£º
Article; Concha, Camila; Quintana, Cristobal; Klahn, A. Hugo; Artigas, Vania; Fuentealba, Mauricio; Biot, Christophe; Halloum, Iman; Kremer, Laurent; Lopez, Rodrigo; Romanos, Javier; Huentupil, Yosselin; Arancibia, Rodrigo; Polyhedron; vol. 131; (2017); p. 40 – 45;,
Iron Catalysis in Organic Synthesis | Chemical Reviews
Iron Catalysis in Organic Synthesis: A Critical Assessment of What It Takes To Make This Base Metal a Multitasking Champion